According to estimates by the WHO, the World Health Organisation,
only about half

of all chronically ill
patients  comply with their doctor's
precise recommendations for taking their medication.

According to studies,
more than six million patients in Germany take more than three drugs daily.

The direct and indirect costs of non-compliance in Germany are estimated at between 
7.5 and 10 billion euros per year.

Compliance rate: for one tablet per day 80 per cent, for four tablets to be taken per day only 30 percent.